CPH analysis of clinical variables associated with OS in the NF1-mutant, IDH wild-type glioblastoma cohort revealed age, KPS (21, 22), multifocality, adjuvant radiation (23, 24), adjuvant temozolomide (25, 26), and tumor-treating fields (27) as being associated with OS (P < 0.1) (Figure 1F). This evidence concerns the gene NF1 and glioblastoma.