We analyzed clinical samples, including peripheral blood (PB), synovial fluid (SF), and synovial tissues, from RA and OA patients to evaluate whether the persistent increases in the levels of inflammatory factors (IL‐6, IL‐8, and CXCL10) in our model correspond to the clinical characteristics of the RA synovium. The gene discussed is CXCL10; the disease is rheumatoid arthritis.