In coculture experiments involving M1 macrophages and HUVECs, the levels of IL‐6, IL‐8, and CXCL10 were increased in the RA‐FME group compared with the OA‐FME group, with significant differences in the levels of IL‐6 (Figure 5B,C,E). The gene discussed is CXCL8; the disease is rheumatoid arthritis.