performed CLI on mice with human epidermal growth factor receptor 2 (HER2)‐positive breast cancer using 89Zr‐desferrioxamine‐trastuzumab for preclinical surgical navigation.[158] The entire process of tumor imaging and complete resection took less than 40 min, indicating that CLI can quickly and accurately locate and identify tumor boundaries and guide tumor resection. The gene discussed is ERBB2; the disease is breast carcinoma.