The single BLEO‐IPF mouse more closely mirrored findings of pulmonary cell senescence in end‐stage human IPF, featuring significantly increased expression of various senescence markers, including Cdkn1a, Cdkn2c, H2afx, Trp53, Il6, Ccr5, and Timp1. This evidence concerns the gene CDKN1A and idiopathic pulmonary fibrosis.