CD8A and invasive breast carcinoma: Analysis of the infiltration abundance of 28 immune cells in BRCA patients revealed that high-risk BRCA patients had higher infiltration of activated CD8 T cells, activated CD4 T cells, activated B cells than the low-risk group, while the infiltration of mast cells, macrophages, and effector memory CD8 T cells was lower in the high-risk group (Fig. 6A), indicating that high-risk BRCA patients had lower immunoreactivity.