SSM: Superficial spreading melanoma; NM: Nodular melanoma; LMM: Lentigo maligna melanoma; ALM: Acral lentiginous melanoma, DM: Desmoplastic melanoma; BRAF: B-Raf proto-oncogene, serine/threonine kinase; KIT: KIT proto-oncogene receptor tyrosine kinase. The gene discussed is BRAF; the disease is melanoma.