PRKD1 and reading: Finally, PRKD1 and correlated genes in rectum adenocarcinoma (READ), using cutoff (0.78), had significant biological processes such as regulation of endothelial cell proliferation (p > 0.001, p > 0.004), regulation of endocytosis (p > 0.006), positive regulation of cell differentiation (p > 0.008), regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (p > 0.01), regulation of angiogenesis (p > 0.03), and regulation of blood vessel endothelial cell migration (p > 0.04) (Figure 18C).