For KICH, the GSE15641 dataset, comprising 23 normal kidney tissue samples and six chromophobe renal cell carcinoma samples, revealed 22,276 DEGs, with 15,223 downregulated and 7,053 upregulated; PRKD1 was downregulated (logFC = -0.4495177, adjusted p = 1.76e-04) (Figure 19B). Here, PRKD1 is linked to chromophobe renal cell carcinoma.