In line with these results, the severity of MASLD assessed by MAS (comprised of liver steatosis, lobular inflammation, and hepatocellular ballooning scores) was similarly decreased in all groups of mice depleted of either STK25, MST3, or STK25/MST3 compared with their respective controls (Fig. 2G, Additional File 2: Supplementary Fig. S5). The gene discussed is STK25; the disease is metabolic dysfunction-associated steatotic liver disease.