F2 and antiphospholipid syndrome: Provoked clots include those caused by transient risk factors (surgery, trauma, immobility, pregnancy or puerperium, hormonal medication use, or COVID-19 infection), while unprovoked clots may be secondary to an underlying hypercoagulable disorder such as protein C/S deficiency, antiphospholipid antibody syndrome, prothrombin gene mutation, or other undefined hypercoagulable states.