The significant SOCs associated with solriamfetol-induced AEs, in which at least one of the four statistical methods (ROR, PRR, BCPNN, and MGPS), included psychiatric disorders (SOC: 10037175); pregnancy, puerperium, and perinatal conditions (SOC: 10036585); nervous system disorders (SOC: 10029205); general disorders and administration site conditions (SOC: 10018065); and cardiac disorders (SOC: 10007541). Here, CISH is linked to nervous system disorder.