We observed altered expression of genes well known to be dysregulated in T2D, including IAPP (Chen et al., 2018; Folli et al., 2018), PAX4 (Lorenzo et al., 2015; Collombat et al., 2003), SLC2A2 (Dupuis et al., 2010), FFAR4 (Wu et al., 2021), and ENTPD3 (Docherty et al., 2021; Syed et al., 2013; Figure 1D, E). This evidence concerns the gene ENTPD3 and type 2 diabetes mellitus.