For ovarian and uterine endometrioid carcinomas, somatic mutation frequencies were similar at nine commonly mutated genes in these tissues, namely TP53, PTEN, PIK3CA, NF1, MYC, KRAS, CTNNB1, BRCA1, and ARID1A (Fig. 5A). The gene discussed is PIK3CA; the disease is endometrial endometrioid adenocarcinoma.