STK11 and colorectal cancer: Germline STK11 inactivating mutations have been associated with Peutz–Jeghers syndrome (52), and somatic changes in this gene have been reported in a variety of cancers, including non–small cell lung cancer, cervical cancer, colorectal cancer, melanoma, and pancreatic cancer with predominantly truncating mutations but have not yet been reported in endometrioid ovarian carcinoma.