Particularly, the lentiviral delivery of the mouse homolog of TRAF3IP2-AS1 (E130307A14-Rik), a regulator of IL-17 signaling, yielded therapeutic effects in an IMQ-induced mouse model of psoriasis, by reducing epidermis thickness, immune cell infiltration, and pro-inflammatory cytokine expression [102]. The gene discussed is IL17A; the disease is psoriasis.