TLR4 and lymphoma: In detail, miR-3960 targets genes such as HOXA2 and RUNX2, which may influence stromal remodeling and extracellular matrix interactions in the lymphoma niche; miR-6089 suppresses TLR4-mediated NF-κB signaling by directly targeting TLR4 mRNA, thus attenuating pro-inflammatory cytokine release facilitating immune evasion.