In any case, (a) infections and/or metabolic disorders must be excluded; (b) magnetic resonance imaging (MRI) must be performed to rule out different and alternative diagnoses; and (c) detection of some auto antibodies (primarily, anti-riboP antibodies, anti-N-methyl-D-aspartate receptor [NMDAR] subunit 2 antibodies, and anti-aPL antibodies) should be carried out. The gene discussed is FASLG; the disease is metabolic disease.