Regarding the influence of acidity, it was found that all alarmin mean concentrations were similar in children with acid reflux (n = 32) and non-acid reflux (n = 36): IL-25 11.9 ± 13.7 pg/mL in acid reflux vs. 15.2 ± 14.9 pq/mL in non-acid reflux (p = 0.362); TSLP—20.0 ± 11.5 pg/mL vs. 21.6 ± 12.9 (p = 0.603); IL-33—6.8 ± 4.7 pg/mL vs. 6.9 ± 5.1 pg/mL (p = 0.953); periostin—5.4 ± 2.0 pg/mL vs. 6.3 ± 3.2 pg/mL (p = 0.168). The gene discussed is POSTN; the disease is gastroesophageal reflux disease.