Likewise, studies employing CCR2 depleter mice result in the depletion of not only CCR2+ monocytes and CCR2+ mo-DCs during A. fumigatus lung infection (14, –, 16) but also potentially inf-cDC2s, as they depend on CCR2 for migrating to the lungs during viral infection (20). This evidence concerns the gene CCR2 and viral infectious disease.