SH3BP2 and infection: In summary, this study provides crucial insights into the resistance mechanisms and transmission dynamics of CRPM, as well as underscores the need to enhance genomic surveillance and optimize infection control strategies to mitigate the spread of <i>bla</i><sub>NDM-1</sub>-harboring CRPMs.<h4>Importance</h4>To date, the phylogeographic distribution of <i>bla</i><sub>NDM</sub>-carrying CRPMs has not been determined.