The dysregulation of blood coagulation during COVID-19 results in depleted circulating PROS1 levels [27], which can consequently contribute to cytokine storm by reducing the immunosuppressive action of MERTK in macrophages [28, 29] and diminishing intrinsic PROS1 anticoagulant function [23, 25, 27, 30]. This evidence concerns the gene MERTK and COVID-19.