Mutations in several AChR subunit genes have been associated with genetic forms of arthrogryposis (CHRNA1, CHRNB1, CHRND, CHRNE, CHRNG).30 AMC is a condition recognized in the neonatal period by the presence of multiple congenital contractures associated with muscle weakness throughout the body.31 AMC is characterized by primary skeletal muscle involvement followed by brain involvement, with the most common associated neurological symptoms being epilepsy, intellectual disability and brain malformations.6 Our patient presented with fetal hypokinesia and arthrogryposis. This evidence concerns the gene CHRND and cerebral malformation.