Among diabetic patients, chronic kidney disease (CKD) is a serious health issue with studies reporting a high prevalence (20–50%) among type-II diabetics.1 In Pakistan, approximately 21.2% of the population is affected by CKD, predominantly males and adults over 50 years old, with diabetic nephropathy as the leading cause.2 CKD in diabetic patients often leads to anemia due to decreased Erythropoietin (EPO) production, disrupted iron metabolism, and chronic inflammation. This evidence concerns the gene EPO and anemia (phenotype).