As a result, 12 variables were selected as features for the subsequent ML model construction: age, a history of hypertension, a history of hyperlipidemia, SBP, number of coronary lesions, NT-proBNP, left ventricular ejection fraction (LVEF), left atrium diameter (LAD), interventricular septal end-diastolic thinkness (IVSd), right ventricular end-diastolic diameter (RVDd), QRS interval, and PLT count. The gene discussed is NPPB; the disease is hyperlipidemia.