Thirteen variables were considered important in relation to all-cause mortality in elderly CHF patients, including age, BNP, cholinesterase, total triiodothyronine, LVEF, total bilirubin, albumin/globulin, estimated glomerular filtration rate (eGFR), hemoglobin, alkaline phosphatase, basophil, hypersensitive C-reactive protein (hsCRP) and D-dimer (Figure 1a). The gene discussed is ALB; the disease is congestive heart failure.