AFP and hepatocellular carcinoma: For instance, Nahon et al.5 developed a multi-aetiology score (FASTRAK) dedicated to European patients with cirrhosis and no viral replication based on age, sex, platelet count, total bilirubin, GGT, and serum α-foetoprotein (AFP) that achieved a Harrell’s c-index up to 0.76 to identify patients with an annual risk of HCC over 3% after 3 years of follow-up.5