However, upon completion of the infusion, the patient again developed alterations of the coagulation parameters: a grade 3 thrombocytopenia (almost 25 × 109/L), prolonged prothrombin (18.4 s; normal range 12.0–15.0 s) and aPTT times (36.5 s; normal range 24.0–31.0 s), and a reduction in the fibrinogen level (1.5 g/L; normal range 2.0–4.0 g/L) and an increase in D-dimer (>20.00 μg/mL; normal range 0.0–0.5 μg/mL) were observed. The gene discussed is F2; the disease is Thrombocytopenia.