In a variety of malignant tumors, the expression level of ASPM is significantly elevated, which is closely related to the progression of various tumors, including prostate cancer (Pai et al., 2019), lung cancer (Cheng et al., 2023), bladder cancer (Xu et al., 2019), and kidney cancer (Deng et al., 2022). The gene discussed is ASPM; the disease is urinary bladder cancer.