ACE and familial hypercholesterolemia: Pears, an old and new fruit, have phytochemicals that show beneficial effects on various diseases and have a strong potential against hyperglycemia, hypercholesterolemia, and hypertension by affecting responsible factors such as inhibiting α‐glucosidase, enhancing GLUT4 mRNA gene expression, and inhibiting ACE and adjusting serum SOD and TBARS.