Alpha‐fetoprotein (AFP) is involved in the cell growth, differentiation, and apoptosis; moreover, people with HCC indicate elevated levels of AFP and a declining number of dendritic cells result in decreased interleukin 12 (IL‐12), which is tangled in the activation of receptors on natural killer (NK) cells known for killing of neoplastic cells (Fox et al. 2022; Geong et al. 2019). Here, AFP is linked to hepatocellular carcinoma.