However, note that there were relevant gene homologs in CBD-treated animals such as opposing regulations of Nlrc5 and Gbp3 in CBD-treated 3xTg-AD mice (Supplementary Table 27) vs. Nlrc4 and Gbp2b, respectively, in 3xTg-AD vehicle vs. wild-type mice (Supplementary Table 25). Here, GBP3 is linked to Alzheimer disease.