EDNRB and Alzheimer disease: Of the DEGs marked with AD in 3xTg-AD animals as common with wild-type animals (Figures 1A, B, Supplementary Tables 1, 2) and CBD-treated 3xTg-AD animals (Figure 1C, Supplementary Table 6), 6 were regulated in the same direction as Pdk4, C1qb, C1qc, Ptgis, C4b, and Ednrb in CBD-treated wild-type animals (Figure 1D, Supplementary Table 9).