In particular, excessive sleep is associated with elevated levels of inflammatory markers such as interleukin-6 (IL-6) and C-reactive protein (CRP) (Irwin et al., 2016; Dolsen et al., 2021; Iakunchykova et al., 2024), suggesting that the inflammatory pathway may play an important role in HL related to excessive sleep. This evidence concerns the gene IL6 and Hodgkins lymphoma.