CSF3 and neoplasm: For example, G‐CSF, as an important stimulator of neutrophil release, promotes the mobilization of neutrophils from the BM to the circulatory system and also prolongs the lifespan of neutrophils through inhibition of apoptosis, allowing for an expanded role, whereas tumor‐derived TGF‐β in the TME promotes the polarization of TANs into N2‐type TANs [153, 156].