MPO and neoplasm: By quantitatively detecting NETs or derivatives of NETs such as MPO‐DNA, NE‐DNA, or Circ‐DNA, the prognosis of the tumor can be reflected a certain extent, and H3Cit, as a representative marker of chromatin depolymerization in the process of NETs formation, can also be used as a prognostic indicator for cancer patients [64, 233, 234].