This study aims to describe the distinct lipoprotein profile in active and remission RA population, in an effort to globally map the effect of inflammation and disease activity on the metabolome and determine the association of lipoproteins and their subclasses with clinical parameters currently in use to monitor RA patients, including DAS28, acute phase reactant CRP, but also Visual Analogue Scale of pain (VAS). Here, CRP is linked to rheumatoid arthritis.