DMD results from loss-of-function mutations in the dystrophin (DMD) gene, eliminating dystrophin, a critical cytoskeletal protein that connects the intracellular actin cytoskeleton to the extracellular matrix (ECM) via the dystrophin-associated protein complex (DAPC) (Duan et al., 2021). This evidence concerns the gene DNM2 and Duchenne muscular dystrophy.