IRF2BP2 and cancer: IRF2BP2 (interferon regulatory factor 2 binding protein 2) is a gene commonly involved in apoptosis, survival, cell differentiation, cancer development, and immune response [2]. The CDX1 (caudal-type homeobox 1) gene has a role in regulating enterocyte differentiation, expression of the intestinal alkaline phosphatase gene, and inhibiting beta-catenin/T-cell factor transcriptional activity [3].