IRF2BP2 and myoepithelial tumor: Herein, we report a novel gene fusion, IRF2BP2::CDX1, in a myoepithelial tumor of soft tissue in a 36-year-old female harboring rare morphologic findings, including multinucleated giant cells and microhemorrhages. Our case adds to the expanding pool of EWSR1-negative myoepithelial tumors of soft tissue.