CP and type 2 diabetes mellitus: As expected due to decreased renal clearance, the mean circulating CP value in our sample (4 ± 5 ng/mL) was higher than the range of values previously reported in healthy people (0.36–3.61 ng/mL) (31) and in patients with T2DM at milder stages of CKD (~0.6–3 ng/mL) (32).