mTOR inhibitors, such as sirolimus and everolimus, target the mechanistic target of the rapamycin(mTOR) pathway, which plays a crucial role in regulating immune cell activation, proliferation and differentiation [37].These drugs can modulate the immune response by inhibiting mTOR, which may result in a more balanced and controlled immune response toviral infections [38]. The gene discussed is MTOR; the disease is infection.