Numerouspro-inflammatory mediators, such as tumor necrosis factor (TNF), Interleukin-1 (IL-1), IL-8 and IL-6 are produced by cells in thegingival tissue [10, 11-12].In an attempt to manage the resulting infection and preserve the equilibrium of the equilibrium of the tissues, these cytokines play arole in attracting and stimulating inflammatory cells, thereby permitting the regeneration of tissue and healing [13,14-15]. This evidence concerns the gene TNF and infection.