Thecancer-promoting effects of IL-6 occur through three main mechanisms which involve creation of new blood vessels and prevention of cellsuicide along with increased tumor cell growth [2, 3].Research investigating OSCC shows tissue, serum and saliva samples of affected patients have elevated IL-6 concentrations which indicateits contribution to tumor biology yet demonstrates its diagnostic potential [4,5-6]. The gene discussed is IL6; the disease is neoplasm.