Additionally, by integrating data from ATC-containing samples in the NCBI database, we found that GSDME (DFNA5) was significantly upregulated in ATC samples compared to normal thyroid (NT) and other types of thyroid cancer, whereas GSDMD did not exhibit a consistent upregulation trend (Figures 4C,D). The gene discussed is GSDME; the disease is thyroid gland carcinoma.