For instance, survivin plays a role in cell division and apoptosis inhibition (Yesupatham et al., 2023; Ju et al., 2017), while glucose-regulated protein 78 (GRP78) mediates tumor metastasis (Lizardo et al., 2016), proliferation (Yin et al., 2017), and resistance to chemotherapy and radiotherapy (Gu et al., 2015). The gene discussed is HSPA5; the disease is neoplasm.