colonization was independently reported as a risk factor for the occurrence of acute Graft versus Host Disease (GVHD), irrespective of the patients’ Dectin-1 status.25 While Dectin-1 deficiency might result in diminishing patients’ immunity, leading to GVHD, the effect was observed to be indirect in addition to Candida spp. Here, CLEC7A is linked to acute graft versus host disease.