Mesenchymal stem cell-induced lncRNA Hcp 5 drives fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis, promoting chemotherapy resistance in GC cells, indicating that targeting Hcp 5 is a new approach to enhance the efficacy of GC chemotherapy drugs (14). Here, PPARGC1A is linked to gastric cancer.