To further investigate the effect target of ACOT11 on miR-1343-3p and determine the miR-1343-3p/ACOT11/FFA lipid metabolism signaling pathway as a potential effect target of salidroside’s anti-tumor effect, miR-1343-3p mimic and miR-1343-3p inhibitor were designed and transfected into GC cells. Here, ACOT11 is linked to gastric cancer.