Tian Tian J J Chen Chen JH JH Chao Chao SX SX Pelka Pelka K K Giannakis Giannakis M M Hess Hess J J Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial Nat Med Nat Med 2023 2023 29 29 458 458 66 66 10.1038/s41591-022-02181-8 10.1038/s41591-022-02181-8 36702949 36702949. The gene discussed is BRAF; the disease is colorectal cancer.