Several studies have further suggested that specific allelic variants in GABRB2 may influence schizophrenia-related features, including disease occurrence and age at onset (Lo et al., 2007a, Chen et al., 2009), symptom severity and required antipsychotic dosage, as well as aspects of social cognition (Tsang et al., 2013), although these associations remain inconsistent across different populations. This evidence concerns the gene GABRB2 and schizophrenia.