Minichromosome Maintenance Complex Component 10 (MCM10) (148), overexpressed 4.2-fold in resistant tumors, activates Aldehyde Dehydrogenase 1 Family Member A1(ALDH1A1) and SRY-Box Transcription Factor 2 (SOX2) to promote stemness, evidenced by tumor sphere enlargement. This evidence concerns the gene ALDH1A1 and neoplasm.