The overrepresentation of the genetic risk variants of PTPN6, IL-10, IL-1β, and DNMT1 genes in RA was found to be upregulated, while PTPRC, CCR6, and IL-6 genes (Figure 2) were downregulated according to eQTL (https://gtexportal.org/home/datasets). This evidence concerns the gene CCR6 and rheumatoid arthritis.