For the protein targets, we selected few of the most researched key proteins involved in cancer pathways from the GDSC database, as listed below: EGFR (Pathway: EGFR signaling, UniProt: P00533), Tyrosine-protein kinase ABL1 (Pathway: ABL signaling, UniProt: P00519), Serine/threonine-protein kinase mTOR (Pathway: P13K/MTOR signaling, UniProt: P42345), Cellular tumor antigen p53 (Pathway: P53, UniProt: P04637), Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) (Pathway: ERK/MAPK signaling, UniProt: Q13233). This evidence concerns the gene TP53 and cancer.