PRKN and neuroblastoma: shRNA-mediated knockdown of ANKRD13A in neuroblastoma cell line SH-SY5Y expressing the mitophagy flux reporter resulted in a significantly reduced OA-induced mitophagy flux (Fig. 2, H and I), indicating that ANKRD13A is also important for mitophagy when Parkin is expressed at endogenous, physiologically relevant levels.