Both conditions are marked by enhanced CD8+ T cell infiltration,[20] interferon‐gamma (IFN‐γ) pathway activation,[21] and chemokine‐driven recruitment of effector T cells, including C─X─C motif chemokine 9 (CXCL9), C─X─C motif chemokine 10 (CXCL10), and CCL5.[22, 23, 24] Moreover, both vitiligo lesions and T cell–inflamed tumors exhibit elevated expression of antigen presentation machinery, MHC class I molecules, and interferon‐stimulated gene signatures. This evidence concerns the gene CD8A and vitiligo.