BDNF promotes neuronal growth, synaptic plasticity, and cognitive processes including learning and memory.10 The rs6265 polymorphism in the BDNF gene alters the intracellular processing of BDNF, affecting its secretion.11BDNF also influences neurotransmitters such as serotonin and dopamine, impacting the body reward system.11 This polymorphism is associated with a decreased risk of alcohol dependence, while the homozygous wild-type genotype increases susceptibility to alcohol addiction.11 The gene discussed is BDNF; the disease is Addictive alcohol use.